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    • Massimo livi BacciMassimo livi Bacci
      Emeritus Professor of Demography, University of Florence, Italy
      Jacques VallinJacques Vallin
      Emeritus Research Director at INED, Paris; Honorary President of IUSSP
      Alaka BasuAlaka Basu
      Alaka M. Basu is Professor, Development Sociology, Cornell University, and a member of the Guttmacher-Lancet Commission on Sexual and Reproductive Rights and Health
      Bruno MasquelierBruno Masquelier
      Professor of Demography, University of Louvain, Belgium
      Gustavo De SantisGustavo De Santis
      Professor of Demography, University of Florence, Italy
      Ernestina CoastErnestina Coast
      Associate Professor of Population Studies, London School of Economics
      Roberto ImpicciatoreRoberto Impicciatore
      Assistant Professor of Demography, University of Milan, Italy
      Salvatore StrozzaSalvatore Strozza
      Professor of Demography, University Federico II, Naples (Italy)
      Cinzia ContiCinzia Conti
      Researcher at Istat, Head of Unit on Foreign Presence and Social Dynamics
      Alessandro RosinaAlessandro Rosina
      Professor of Demography and Director, Center for Applied Statistics in Business and Economics, Università Cattolica del Sacro Cuore
      Letizia MencariniLetizia Mencarini
      Associate professor of Demography, Bocconi University - Dondena Centre for Research on Social Dynamics and Public Policy & Collegio Carlo Alberto; P.I. ERC P.I. ERC project n. 313617 (2013-2018) SWELLFER http://swellfer.wordpress.com
      Feng WangFeng Wang
      Professor of Sociology at the University of California, Irvine, USA, and Professor at Fudan University, Shanghai, China
      Corrado BonifaziCorrado Bonifazi
      Director of the Institute for Research on Population and Social Policies, National Research Council, Rome Italy
      John KnodelJohn Knodel
      Research Professor Emeritus, Population Studies Center, Institute for Social Research, University of Michigan (USA) and International staff, College of Populations Studies, Chulalongkorn University (Thailand)
      Gilles PisonGilles Pison
      Professor at Museum National d'Histoire Naturelle and Director of Research at the French National Institute for Demographic Studies (INED) (Paris)
      Andrea BrandoliniAndrea Brandolini
      Head of Statistical Analysis Directorate, Bank of Italy
      Peter McDonaldPeter McDonald
      Professor of Demography in the Australian National University. Honorary President of IUSSP and winner of the Irene B. Taeuber Award
      Monica Das GuptaMonica Das Gupta
      Research Professor of Sociology, University of Maryland, USA
      Stefano MolinaStefano Molina
      Senior Program Officer, Giovanni Agnelli Foundation, Italy
      Cheikh MbackéCheikh Mbacké
      Associate Professor, Sociology department, Laval University
      Letizia TanturriLetizia Tanturri
      Associate Professor of Demography, University of Padova, Italy
      Francesco BillariFrancesco Billari
      Professor of Sociology and Demography, University of Oxford
      Paula Miranda-RibeiroPaula Miranda-Ribeiro
      Professor, Demography Department and Cedeplar, Universidade Federal de Minas Gerais, Brazil.
      our authors
  • N-IUSSP
    • N-IUSSP is a new IUSSP news magazine, which will disseminate scientific findings from demographic research carried out all over the world. The practical implications of current trends, the risks and potentialities of emerging situations, the pros and cons of specific laws are discussed in rigorous but plain language.

      You are invited to contribute to this new publication: please check our guidelines and submit your 1000 word contribution to contact@niussp.org

Dementia risk on the rise as old-age life expectancy increases
Le risque de démence augmente à mesure que l’espérance de vie s’allonge

Ezra Fishman
man affected with dementia

As America’s population ages, the number of Americans with dementia is increasing. Because people with dementia often need help with activities of daily living, the cost of caring for a person with dementia for one year is about $28,500 on average (Hurd et al. 2013). For elders who have spent down their savings, Medicaid covers the costs of long-term care needed by many people with dementia. Given the aging population, long-term care is likely to contribute to increased spending in Medicaid (Keehan 2017). What fraction of adults will develop dementia in their lifetimes? Another way of asking the same question is, what is the probability that an average dementia-free person of a given age will develop dementia in his/her lifetime? I explored this question in a recent paper (Fishman 2017). The answer depends on both death rates and rates of developing dementia.

The probability of developing dementia

The incidence rate of dementia is defined as the number of new people diagnosed with dementia for every 1,000 people living a year without dementia in a given population. Table 1 shows that the dementia incidence rate increases rapidly with age, from about 10 per 1,000 at age 70 to about 130 per 1,000 at age 100. Schermata 2018-01-12 alle 09.11.25

Of course, death rates also increase rapidly with age, so many people will die before they develop dementia. At the same time, death rates at any given age are lower than in the past. Table 2 (top) combines these facts to show that among males born in 1920, about 27% of dementia-free 70-year-olds developed dementia in their remaining lifetimes, and this percentage goes down only slightly with age. Schermata 2018-01-12 alle 09.13.01For males born in 1940, a larger proportion are expected to develop dementia in their lifetimes, because a larger fraction will survive to very old ages.

Table 2 (bottom) shows that the same is true for females. Because females tend to live longer than males, at any given age the proportion of females expected to develop dementia in their lifetime is higher than the proportion for males. This is true even though the incidence rates shown in Table 1 apply to both males and females. About 35% of 70-year-old females born in 1920 developed dementia, compared to 37% for 70-year-old females born in 1940.
It is imperative to note that as mortality has declined across generations, the proportion of people who will develop dementia in their lifetimes has increased; this has important implications for society.

Government programs and individual families will face challenges caring for elders with dementia

Savings are low for many American households: in 2016, about 20% of Americans aged 45 and older lacked any retirement savings (Board of Governors of the Federal Reserve 2017). Given the increase across generations in the proportion of adults who develop dementia before death, Medicaid might expect to see increases in enrollment in the coming decades.
Although Medicaid could play an increasing role, family members provide most of the care needed by persons with dementia (Hurd et al. 2013). People who care for relatives with dementia face greater health risks than contemporaries who care for family members without dementia, and these health risks persist even after the relatives have died (Dassel and Carr 2016; Fisher et al. 2011).

One important implication of our study results is that elderly persons do not “age out” of the risk of developing dementia. Yet, as individuals age, they are decreasingly likely to have surviving spouses who are able to care for them. This means that adult children, especially daughters (Fisher et al. 2011; Kasper et al. 2015), increasingly shoulder dementia caregiving responsibilities for long durations, with potential negative consequences for their own mental health (Fisher et al. 2011) and labor force participation (Hurd et al. 2013).

Reasons for optimism

Table 3 shows that if a medical, behavioral, or environmental intervention were developed that delays dementia onset by 5 years and reaches 90% of the older-age population, the probability of developing dementia would drop a great deal. Schermata 2018-01-12 alle 09.14.10Comparing males and females born in 1920 (Table 2) to Table 3 below, such an intervention would reduce the lifetime risk of developing dementia by about 25% (7 to 8 percentage points). Given the high economic and personal cost of dementia caregiving, such a reduction would represent a substantial social gain.

Recent evidence has shown that dementia incidence declined from the 1970s to the 2000s among subjects in a multi-generational public-health study in Massachusetts (Satizabal et al. 2016). And recent research suggests this decline in dementia incidence might have occurred nationally as well. Nobody knows exactly why: “increasing educational attainment and better control of cardiovascular risk factors may have contributed to the improvement, but the full set of social, behavioral, and medical factors contributing to the improvement is still uncertain” (Langa et al. 2017). Those trends, as well as a large recent increase in funding for research on dementia and Alzheimer’s disease (NIH 2017), are reasons for considerable optimism.

References

Board of Governors of the Federal Reserve System. (2017). Report on the Economic Well-Being of U.S. Households in 2016. www.federalreserve.gov/publications/default.htm, accessed October 26, 2017.

Dassel, K. B., & Carr, D. C. (2016). Does Dementia Caregiving Accelerate Frailty? Findings From the Health and Retirement Study. The Gerontologist, 56(3), 444–450. doi:10.1093/geront/gnu078

Fisher, G. G., Franks, M. M., Plassman, B. L., Brown, S. L., Potter, G. G., Llewellyn, D., et al. (2011). Caring for individuals with dementia and cognitive impairment, not dementia: findings from the aging, demographics, and memory study. Journal of the American Geriatrics Society, 59(3), 488–94. doi:10.1111/j.1532-5415.2010.03304.x

Fishman, E. (2017). Risk of developing dementia at older ages in the United States. Demography, 54(5), 1897-1919. https://doi.org/10.1007/s13524-017-0598-7.

Hurd, M. D., Martorell, P., Delavande, A., Mullen, K. J., & Langa, K. M. (2013). Monetary Costs of Dementia in the United States. New England Journal of Medicine, 368(14), 1326–1334. doi:10.1056/NEJMsa1204629

Kasper, J. D., Freedman, V. A., Spillman, B. C., & Wolff, J. L. (2015). The Disproportionate Impact Of Dementia On Family And Unpaid Caregiving To Older Adults. Health Affairs, 34(10), 1642–1649. doi:10.1377/hlthaff.2015.0536

Keehan SP, Stone DA, Poisal JA, Cuckler GA, Sisko AM, Smith SD, Madison AJ, Wolfe CJ, Lizonitz JM. (2017). National Health Expenditure Projections, 2016-25: Price Increases, aging push sector to 205 of economy. Health Affairs. 36(3):553-563. Doi: 10.1377/hlthaff.2016.

Langa KM, Larson EB, Crimmins EM, Faul JD, Levine DA, Kabeto MU, Weir DR. (2017). A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012. JAMA Internal Medicine 177(1):51–58. doi:10.1001/jamainternmed.2016.6807

National Institutes of Health (NIH). (2017). Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC). https://report.nih.gov/categorical_spending.aspx, accessed October 28, 2017.

Satizabal, C. L., Beiser, A. S., Chouraki, V., Chêne, G., Dufouil, C., & Seshadri, S. (2016). Incidence of Dementia over Three Decades in the Framingham Heart Study. New England Journal of Medicine, 374(6), 523–532. doi:10.1056/NEJMoa1504327

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